Cervical cancer is one of the few tumours medicine can stop before it appears, and cytology — the Pap test — is the tool that makes it possible. But screening only works if it reaches ever...
The sexual development of an embryo does not depend on a single instruction, but on a chain of signals that must fire in the right order and the right place. When one link in that chain fails, develop...
Every year, thousands of transgender men go through surgery for a hysterectomy with removal of the ovaries and fallopian tubes as part of their medical transition. Before that operation they have spen...
Gender-affirming surgeries have risen markedly over the past fifteen years, yet reversing those procedures remains a poorly understood and, above all, poorly framed field. A new case report in Annals ...
Erasing identity does not heal: that is the conclusion pointed to by the largest systematic review assembled to date on so-called “conversion therapies,” the practices that seek to force a...
Twenty fingers pressing on the arm of the clinic chair. An electrocardiogram. A blood test with fifteen parameters. And the same question as always: what is testosterone doing to my body, year after y...
How can we know whether a gender-affirming hormone dose is right? Until now, the answer has relied largely on clinical experience and on each person’s symptoms. A new study published in the jour...
A clinical study published in JCEM Case Reports describes two sisters born with atypical sex development whose origin has just been traced to a genetic mutation never described before. The case serves...
The immune system is the body’s network of defenses. And, like many other functions, it also shifts when a transgender person starts gender-affirming hormone therapy. A team from Ghent Universit...
A large national follow-up in the United States suggests that gender-affirming medical care is associated with a significant reduction in posttraumatic stress symptoms among transgender and gender-exp...
For many transgender women, the voice is one of the hardest fronts of transition. Although hormone therapy produces visible changes in the body, it does not by itself change the pitch of the voice, be...
Gender-affirming hormone therapy is the cornerstone of treatment for many transgender people, but its effects go far beyond the visible changes: they also reach internal organs such as the kidney. A n...