Gender-affirming hormone therapy visibly changes the body of transgender women, but what happens inside, at the molecular level, had remained largely a mystery. An international team has this time loo...
One of the questions that worries people starting gender-affirming hormone therapy most is that of cardiovascular risk. In transgender women it has long been known that oestrogen can raise the likelih...
Differences in sex development (DSD) — also known as intersex traits — are a set of congenital conditions in which chromosomal, gonadal or anatomical development does not follow the typically male or ...
How and when gender identity takes shape is one of the central questions in research on gender dysphoria. A new study based on data from the largest Chinese national survey on transgender health, publ...
The medical treatment of gender affirmation in adolescents — defined as the period from the onset of puberty until the age of 18 — has become one of the most debated areas of medicine today. An articl...
Does the brain of a transgender woman resemble more that of the people who share her gender identity, or that of those who share her sex assigned at birth? It is one of the classic questions in the ne...
Is the brain of a transgender person more similar to the sex assigned at birth, or to the gender they identify with? It is one of the central questions in the neuroscience of gender dysphoria, and a n...
A new study, funded by the World Health Organization, has brought together the available evidence on healthcare for adults with gender incongruence. The main conclusion is clear: the medical care thes...
In the collective imagination, breast cancer is almost always associated with a particular patient profile. But the clinical reality is much broader and, for years, data on this disease in transgender...
The human body does not treat testosterone and oestradiol as mere messengers of reproduction: these hormones travel throughout the organism and also communicate with the immune system. A group of rese...
On average, how long does a transgender person live compared with the rest of the population? Until now, the answers were based mainly on small studies or studies from specific countries. A new nation...
What happens to the mental health of adolescents who attend specialised gender identity services? A nationwide study carried out in Finland, published in Acta Paediatrica, has analysed medical records...