For a long time, sex has been discussed as if it were a switch that can only be in two positions. The genetics of development, however, tells a more nuanced story. An international team coordinated by...
Gender-affirming hormone therapy has been the subject of debate for years, and one of the questions that most concerns the medical community is its effect on the heart and blood vessels. New research ...
Adolescence is the critical window in which most of the bone mass of a lifetime is accumulated. That is why any treatment that interferes with this process raises legitimate doubts. A new meta-analysi...
During adolescence, the body experiences one of the greatest hormonal reorganizations of life. For young people with gender dysphoria, that process can become an intense source of distress. A question...
What happens to the set of proteins circulating in the blood when a transgender person begins feminizing hormone therapy? An international team led from the Murdoch Children’s Research Institute...
A new review study published in 2026 in the journal Journal of Pediatric Urology (Elsevier) analyzes the relationship between congenital adrenal hyperplasia and gender dysphoria. Congenital adrenal hy...
The biological basis of gender incongruence remains a mystery, but the accumulated evidence points to hormonal and environmental factors acting during fetal development as potentially playing a releva...
A study published in 2026 in the journal Scientific Reports (from the Nature group) offers new data on the brain activity of transgender women, a group for which neuroscientific evidence remains scarc...
The voice is one of the most visible markers of gender identity, and having it align with each person’s lived gender profoundly influences their psychological well-being. A new study published i...
Sex hormones influence many bodily processes beyond sexual characteristics, and one of the most relevant is insulin sensitivity—that is, the ability of cells to respond to this hormone and take up glu...
Hormone therapy is one of the cornerstones of gender-affirming treatment in people with gender incongruence, but many questions remain open about its medium- and long-term effects on health. A team fr...
A new study published in 2026 in the journal Dialogues in Clinical Neuroscience provides one of the most detailed descriptions to date of how brain circuits are organized in people with gender incongr...